Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.727


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPAchr21_+_260296020.861.8e-05Click!
ELK1chrX_-_473948080.731.3e-03Click!
GABPB1chr15_-_484345670.467.1e-02Click!
ELK4chr1_-_2038674020.332.2e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_99536214 5.031 NM_182776
MCM7
minichromosome maintenance complex component 7
chr13_-_45654296 4.726 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_38046270 4.444 YRDC
yrdC domain containing (E. coli)
chr3_+_181802592 4.324 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr12_+_118590039 4.048 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_38046433 3.894 YRDC
yrdC domain containing (E. coli)
chr1_-_38046410 3.884 YRDC
yrdC domain containing (E. coli)
chr10_-_43212681 3.752 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr7_-_128482059 3.746 TNPO3
transportin 3
chr21_-_32906729 3.731 NM_021254
C21orf59
chromosome 21 open reading frame 59
chr7_-_128482354 3.484 TNPO3
transportin 3
chr7_-_2248315 3.462 FTSJ2
FtsJ homolog 2 (E. coli)
chr13_-_45654327 3.408 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_32906528 3.284 C21orf59
chromosome 21 open reading frame 59
chr6_+_170705345 3.232 NM_001172085
NM_003194
TBP

TATA box binding protein

chr9_-_137992766 3.218 UBAC1
UBA domain containing 1
chr1_-_38228179 3.215 NM_006802
SF3A3
splicing factor 3a, subunit 3, 60kDa
chr7_-_2248348 3.204 NM_013393
FTSJ2
FtsJ homolog 2 (E. coli)
chr4_+_110956085 3.196 NM_018983
NM_032993
GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr9_-_137992967 3.191 NM_016172
UBAC1
UBA domain containing 1
chr1_-_220829704 3.157 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr1_-_52642646 3.148 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr5_+_945950 3.148 NM_001166260
NM_004237
TRIP13

thyroid hormone receptor interactor 13

chr4_+_110956360 3.146 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr4_-_159863889 3.117 NM_005038
PPID
peptidylprolyl isomerase D
chr1_-_38046439 3.073 NM_024640
YRDC
yrdC domain containing (E. coli)
chr16_-_67930974 3.070 NM_032382
COG8
component of oligomeric golgi complex 8
chr10_-_43212703 3.037 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr4_-_140224794 2.988 ELF2
E74-like factor 2 (ets domain transcription factor)
chr20_+_60395515 2.981 NM_001024
RPS21
ribosomal protein S21
chr6_+_30632641 2.928 PRR3
proline rich 3
chr7_-_134506001 2.918 C7orf49
chromosome 7 open reading frame 49
chr1_-_244796169 2.894 NM_022366
TFB2M
transcription factor B2, mitochondrial
chr16_+_67931178 2.792 NIP7
nuclear import 7 homolog (S. cerevisiae)
chr7_-_134506012 2.779 C7orf49
chromosome 7 open reading frame 49
chr8_+_145205555 2.770 EXOSC4
exosome component 4
chr14_+_100270222 2.741 DLK1
delta-like 1 homolog (Drosophila)
chr7_-_134505923 2.735 C7orf49
chromosome 7 open reading frame 49
chr1_-_154964812 2.683 ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr18_+_19287261 2.659 RIOK3
RIO kinase 3 (yeast)
chr21_+_44351681 2.648 PWP2
PWP2 periodic tryptophan protein homolog (yeast)
chr1_-_884483 2.645 NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
chr1_-_884514 2.586 NM_015658
NOC2L
nucleolar complex associated 2 homolog (S. cerevisiae)
chr11_+_6459183 2.570 NM_012192
FXC1
fracture callus 1 homolog (rat)
chr1_-_1300416 2.567 NM_001127230
NM_001127229
AURKAIP1

aurora kinase A interacting protein 1

chr2_+_118288754 2.538 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr1_-_1300680 2.520 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr1_+_168030798 2.470 C1orf112
chromosome 1 open reading frame 112
chr7_-_128482417 2.401 NM_001191028
NM_012470
TNPO3

transportin 3

chr15_+_89061579 2.369 NM_000057
BLM
Bloom syndrome, RecQ helicase-like
chr5_-_37406939 2.357 NM_153485
NUP155
nucleoporin 155kDa
chr1_+_118273887 2.351 NM_006784
WDR3
WD repeat domain 3
chr6_-_33365264 2.337 NM_001164267
NM_005452
WDR46

WD repeat domain 46

chr12_+_68265469 2.308 NM_006431
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr16_+_711139 2.299 NM_023933
FAM173A
family with sequence similarity 173, member A
chr12_+_68265535 2.295 CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr1_-_244796062 2.293 TFB2M
transcription factor B2, mitochondrial
chr11_+_60886407 2.287 TMEM138
transmembrane protein 138
chr11_-_116163948 2.287 NM_003904
ZNF259
zinc finger protein 259
chr22_+_20350272 2.277 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr6_+_30633029 2.267 PRR3
proline rich 3
chr10_+_27026563 2.260 NM_014317
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_+_32460597 2.255 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr16_-_1763036 2.250 NM_023936
MRPS34
mitochondrial ribosomal protein S34
chr6_-_125664913 2.246 NM_016063
HDDC2
HD domain containing 2
chr9_+_99435900 2.246 NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr1_+_32460600 2.217 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr6_+_33365386 2.194 NM_001185181
PFDN6
prefoldin subunit 6
chr22_-_18484428 2.179 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr16_+_29582065 2.173 SPN
sialophorin
chr16_-_67930907 2.170 COG8
component of oligomeric golgi complex 8
chr11_-_116163940 2.152 ZNF259
zinc finger protein 259
chr1_+_32460640 2.148 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr2_+_118288753 2.147 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr10_-_43212166 2.139 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr7_-_73306629 2.130 RFC2
replication factor C (activator 1) 2, 40kDa
chr6_-_170735593 2.129 NM_002598
NM_144781
PDCD2

programmed cell death 2

chr6_+_33365328 2.121 NM_014260
PFDN6
prefoldin subunit 6
chr11_-_407324 2.115 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr2_+_176842368 2.103 NM_006554
MTX2
metaxin 2
chr15_+_72620570 2.091 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr8_-_68136881 2.090 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr7_-_73306668 2.077 NM_002914
NM_181471
RFC2

replication factor C (activator 1) 2, 40kDa

chr5_-_137906814 2.071 NM_004730
ETF1
eukaryotic translation termination factor 1
chr2_+_118288724 2.058 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr6_-_33364912 2.056 WDR46
WD repeat domain 46
chr16_+_2672527 2.046 KCTD5
potassium channel tetramerisation domain containing 5
chr11_-_116163904 2.045 ZNF259
zinc finger protein 259
chr7_+_50318801 2.043 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr17_+_46585928 2.035 NME1
non-metastatic cells 1, protein (NM23A) expressed in
chr2_+_172487153 2.031 NM_003642
HAT1
histone acetyltransferase 1
chr5_+_82409072 2.020 NM_003401
NM_022406
NM_022550
XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr1_-_155053124 2.018 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr5_+_102483856 2.009 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr4_-_140224914 2.008 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr2_+_172487219 2.003 HAT1
histone acetyltransferase 1
chr16_+_20725267 2.001 NM_001144924
NM_001199053
NM_030941
LOC81691


exonuclease NEF-sp


chr1_+_45822246 1.999 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr17_-_17125214 1.999 COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
chr1_+_32460557 1.998 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr5_+_157090900 1.985 NM_017872
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr21_+_44109454 1.965 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr6_-_33398656 1.963 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chrX_-_153428621 1.957 G6PD
glucose-6-phosphate dehydrogenase
chr7_+_120416680 1.956 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr2_+_127130209 1.953 GYPC
glycophorin C (Gerbich blood group)
chr13_-_45654292 1.951 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr22_+_17799341 1.943 MRPL40
mitochondrial ribosomal protein L40
chr1_-_51198417 1.928 FAF1
Fas (TNFRSF6) associated factor 1
chr17_-_17125314 1.926 NM_003653
COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
chr1_-_158579583 1.920


chr6_+_33365445 1.910 PFDN6
prefoldin subunit 6
chr21_-_32906326 1.898 C21orf59
chromosome 21 open reading frame 59
chr1_-_158579680 1.896 COPA
coatomer protein complex, subunit alpha
chr4_-_76658503 1.895 RCHY1
ring finger and CHY zinc finger domain containing 1
chr8_+_145553016 1.888 NM_024531
GPR172A
G protein-coupled receptor 172A
chr5_-_37406955 1.887 NUP155
nucleoporin 155kDa
chr12_+_130761548 1.884 SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr6_+_30693464 1.882 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chrX_+_128867757 1.867 NM_001166221
NM_006649
UTP14A

UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)

chr16_+_2672476 1.863 NM_018992
KCTD5
potassium channel tetramerisation domain containing 5
chr16_+_67931033 1.858 NM_016101
NIP7
nuclear import 7 homolog (S. cerevisiae)
chr12_+_99185334 1.858 NM_017988
SCYL2
SCY1-like 2 (S. cerevisiae)
chr1_-_51198383 1.854 FAF1
Fas (TNFRSF6) associated factor 1
chr14_-_23727850 1.842 NM_024658
IPO4
importin 4
chr2_-_73817935 1.842 NM_016058
TPRKB
TP53RK binding protein
chr16_+_20725511 1.837 LOC81691
exonuclease NEF-sp
chr5_-_37406835 1.833 NUP155
nucleoporin 155kDa
chr14_-_23727826 1.833 IPO4
importin 4
chr1_+_39229474 1.826 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr11_-_60430430 1.825 PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr19_-_61324456 1.821 NM_001002836
ZNF787
zinc finger protein 787
chr17_-_37422656 1.815 NM_001144766
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr19_+_41177882 1.806 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr17_-_37422926 1.803 DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr16_-_20725272 1.803 NM_001142725
NM_080663
ERI2

ERI1 exoribonuclease family member 2

chr12_+_92595281 1.799 NM_003805
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_+_104959767 1.794 NM_021930
RINT1
RAD50 interactor 1
chr17_-_59923547 1.790 NM_007215
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr6_-_42124361 1.778 CCND3
cyclin D3
chr8_+_145205478 1.775 NM_019037
EXOSC4
exosome component 4
chr20_-_44426407 1.769 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr22_-_19543069 1.768 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_-_54775625 1.761 NOSIP
nitric oxide synthase interacting protein
chr11_+_384199 1.760 NM_007183
PKP3
plakophilin 3
chr2_+_172487207 1.760 HAT1
histone acetyltransferase 1
chr1_-_170679830 1.752 PIGC
phosphatidylinositol glycan anchor biosynthesis, class C
chr7_-_98844106 1.752 PDAP1
PDGFA associated protein 1
chr9_+_130258223 1.751 ODF2
outer dense fiber of sperm tails 2
chr7_-_98844151 1.748 PDAP1
PDGFA associated protein 1
chr22_-_21231421 1.742 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr19_-_60483256 1.741 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr10_-_51293220 1.739 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr7_-_45117797 1.731 TBRG4
transforming growth factor beta regulator 4
chr6_+_10803141 1.726 NM_017906
PAK1IP1
PAK1 interacting protein 1
chr2_+_172487246 1.725 HAT1
histone acetyltransferase 1
chr11_-_47826477 1.724 NM_015231
NUP160
nucleoporin 160kDa
chr22_+_38228194 1.724 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr19_-_60483234 1.721 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_+_384238 1.719 PKP3
plakophilin 3
chr8_+_30721208 1.717 NM_005671
UBXN8
UBX domain protein 8
chr19_-_54775603 1.717 NM_015953
NOSIP
nitric oxide synthase interacting protein
chr22_-_17799177 1.711 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr17_+_46585895 1.703 NM_000269
NM_198175
NM_001018136
NME1

NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in

NME1-NME2 readthrough
chr5_-_137906800 1.702 ETF1
eukaryotic translation termination factor 1
chr8_+_145205605 1.693


chr15_+_41879912 1.687 NM_016400
C15orf63
chromosome 15 open reading frame 63
chr8_-_68137102 1.677 NM_006837
COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chrX_-_153368130 1.674 UBL4A
ubiquitin-like 4A
chr11_+_118394637 1.673 TRAPPC4
trafficking protein particle complex 4
chr2_+_85692724 1.672 USP39
ubiquitin specific peptidase 39
chr10_+_12278185 1.672 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr11_-_66925650 1.672 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr9_+_70509925 1.666 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr11_-_60430615 1.659 NM_014502
PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr10_-_22332368 1.654 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr1_-_234834410 1.653 NM_018072
HEATR1
HEAT repeat containing 1
chr19_-_60483302 1.647 NM_001130106
NM_012267
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr22_-_17799215 1.647 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr9_+_130258499 1.645 NM_153433
NM_153440
ODF2

outer dense fiber of sperm tails 2

chr10_+_105146372 1.643 NM_014976
PDCD11
programmed cell death 11
chr7_-_72360722 1.642 NM_001168347
NM_001168348
NM_018044
NM_148956
NSUN5



NOP2/Sun domain family, member 5



chr17_-_37422973 1.638 DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr12_+_67366989 1.637 NM_020401
NUP107
nucleoporin 107kDa
chr16_+_65818511 1.635 NM_014187
TMEM208
transmembrane protein 208
chr19_+_10258642 1.633 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr7_-_91713044 1.630 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr15_+_41880074 1.621 C15orf63
chromosome 15 open reading frame 63
chr1_-_164004611 1.621 TMCO1
transmembrane and coiled-coil domains 1
chr1_-_39111422 1.621 NM_012333
MYCBP
c-myc binding protein
chr19_+_40831061 1.617 COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr10_-_22332600 1.616 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr18_+_19287228 1.615 RIOK3
RIO kinase 3 (yeast)
chr22_-_16637194 1.608 BID
BH3 interacting domain death agonist
chr6_-_125664770 1.597 HDDC2
HD domain containing 2
chr11_-_60953848 1.591 NM_024811
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr5_-_137906707 1.588 ETF1
eukaryotic translation termination factor 1
chr9_-_131637382 1.585 NM_016520
C9orf78
chromosome 9 open reading frame 78
chr12_+_99184977 1.581 SCYL2
SCY1-like 2 (S. cerevisiae)
chr6_+_160068553 1.580 WTAP
Wilms tumor 1 associated protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 2.17e-36 GO:0044260 cellular macromolecule metabolic process
1.55 3.45e-34 GO:0090304 nucleic acid metabolic process
1.45 1.46e-30 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 4.96e-30 GO:0043170 macromolecule metabolic process
2.03 3.01e-29 GO:0006396 RNA processing
1.57 2.11e-28 GO:0016070 RNA metabolic process
2.05 1.17e-25 GO:0016071 mRNA metabolic process
1.51 3.06e-24 GO:0010467 gene expression
2.67 6.31e-24 GO:0000375 RNA splicing, via transesterification reactions
2.67 3.17e-23 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.67 3.17e-23 GO:0000398 nuclear mRNA splicing, via spliceosome
1.22 9.43e-23 GO:0044237 cellular metabolic process
2.33 1.24e-22 GO:0008380 RNA splicing
1.35 5.09e-22 GO:0034641 cellular nitrogen compound metabolic process
2.11 4.72e-20 GO:0006397 mRNA processing
1.33 1.53e-19 GO:0006807 nitrogen compound metabolic process
2.47 4.60e-18 GO:0022613 ribonucleoprotein complex biogenesis
1.18 3.62e-17 GO:0008152 metabolic process
2.40 3.95e-17 GO:0071843 cellular component biogenesis at cellular level
1.19 5.69e-16 GO:0044238 primary metabolic process
1.85 5.92e-13 GO:0016032 viral reproduction
1.30 1.17e-10 GO:0044267 cellular protein metabolic process
1.61 1.97e-10 GO:0022403 cell cycle phase
1.36 4.29e-10 GO:0034645 cellular macromolecule biosynthetic process
1.36 5.51e-10 GO:0009059 macromolecule biosynthetic process
1.48 6.03e-10 GO:0007049 cell cycle
2.38 1.57e-09 GO:0042254 ribosome biogenesis
2.70 3.03e-09 GO:0022618 ribonucleoprotein complex assembly
1.53 3.19e-09 GO:0022402 cell cycle process
1.26 4.51e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.61 7.96e-09 GO:0000278 mitotic cell cycle
1.35 8.30e-09 GO:0006996 organelle organization
1.94 8.55e-09 GO:0034660 ncRNA metabolic process
1.63 2.86e-08 GO:0006974 response to DNA damage stimulus
2.56 4.37e-08 GO:0071826 ribonucleoprotein complex subunit organization
2.15 8.43e-08 GO:0000082 G1/S transition of mitotic cell cycle
2.65 1.11e-07 GO:0006353 transcription termination, DNA-dependent
2.54 1.57e-07 GO:0000216 M/G1 transition of mitotic cell cycle
2.03 3.67e-07 GO:0034470 ncRNA processing
2.27 3.91e-07 GO:0000084 S phase of mitotic cell cycle
1.23 5.81e-07 GO:0019538 protein metabolic process
1.54 9.77e-07 GO:0009057 macromolecule catabolic process
2.23 1.01e-06 GO:0051320 S phase
1.25 1.17e-06 GO:0044249 cellular biosynthetic process
1.58 1.42e-06 GO:0044265 cellular macromolecule catabolic process
1.54 1.82e-06 GO:0006259 DNA metabolic process
1.69 2.32e-06 GO:0010564 regulation of cell cycle process
2.38 2.82e-06 GO:0006364 rRNA processing
1.23 3.29e-06 GO:0009058 biosynthetic process
1.86 7.02e-06 GO:0000075 cell cycle checkpoint
2.30 1.33e-05 GO:0016072 rRNA metabolic process
1.49 1.47e-05 GO:0051726 regulation of cell cycle
2.97 1.51e-05 GO:0006369 termination of RNA polymerase II transcription
1.69 1.74e-05 GO:0051329 interphase of mitotic cell cycle
1.81 2.19e-05 GO:0071156 regulation of cell cycle arrest
1.22 2.28e-05 GO:0071842 cellular component organization at cellular level
1.91 2.41e-05 GO:0006913 nucleocytoplasmic transport
1.68 2.60e-05 GO:0051325 interphase
2.34 3.27e-05 GO:0051168 nuclear export
2.49 3.49e-05 GO:0006302 double-strand break repair
1.89 4.58e-05 GO:0051169 nuclear transport
1.40 5.16e-05 GO:0033554 cellular response to stress
1.19 8.79e-05 GO:0060255 regulation of macromolecule metabolic process
1.41 8.82e-05 GO:0046907 intracellular transport
3.21 1.17e-04 GO:0000387 spliceosomal snRNP assembly
2.19 1.25e-04 GO:0051340 regulation of ligase activity
2.29 1.27e-04 GO:0006354 transcription elongation, DNA-dependent
1.35 1.42e-04 GO:0032774 RNA biosynthetic process
2.42 1.54e-04 GO:0006405 RNA export from nucleus
1.65 1.58e-04 GO:0006412 translation
1.97 2.00e-04 GO:0007005 mitochondrion organization
1.50 2.14e-04 GO:0034621 cellular macromolecular complex subunit organization
2.49 2.43e-04 GO:0006406 mRNA export from nucleus
2.19 2.54e-04 GO:0051438 regulation of ubiquitin-protein ligase activity
3.04 2.65e-04 GO:0000245 spliceosome assembly
1.61 2.73e-04 GO:0006281 DNA repair
1.31 2.86e-04 GO:0044085 cellular component biogenesis
1.17 3.60e-04 GO:0071840 cellular component organization or biogenesis
2.38 3.77e-04 GO:0006368 transcription elongation from RNA polymerase II promoter
2.26 4.19e-04 GO:0006839 mitochondrial transport
2.35 6.39e-04 GO:0072594 establishment of protein localization to organelle
3.05 1.00e-03 GO:0006626 protein targeting to mitochondrion
2.17 1.15e-03 GO:0051351 positive regulation of ligase activity
1.92 1.57e-03 GO:0006403 RNA localization
1.94 1.59e-03 GO:0050657 nucleic acid transport
1.94 1.59e-03 GO:0050658 RNA transport
1.94 1.59e-03 GO:0051236 establishment of RNA localization
2.17 1.65e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.63 2.27e-03 GO:0007346 regulation of mitotic cell cycle
2.17 2.35e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.94 2.43e-03 GO:0072655 establishment of protein localization in mitochondrion
1.56 2.56e-03 GO:0030163 protein catabolic process
1.41 2.75e-03 GO:0051276 chromosome organization
1.86 2.76e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.51 3.25e-03 GO:0000279 M phase
2.11 3.84e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.84 5.52e-03 GO:0070585 protein localization in mitochondrion
1.56 5.57e-03 GO:0006366 transcription from RNA polymerase II promoter
1.92 6.27e-03 GO:0017038 protein import
1.57 6.96e-03 GO:0006511 ubiquitin-dependent protein catabolic process
2.14 7.38e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.22 8.39e-03 GO:0043412 macromolecule modification
1.56 8.67e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.91 8.84e-03 GO:0051028 mRNA transport
1.28 1.05e-02 GO:0044248 cellular catabolic process
1.55 1.14e-02 GO:0019941 modification-dependent protein catabolic process
1.55 1.16e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.81 1.35e-02 GO:0006310 DNA recombination
1.49 1.41e-02 GO:0034622 cellular macromolecular complex assembly
2.30 1.47e-02 GO:0006521 regulation of cellular amino acid metabolic process
2.13 1.51e-02 GO:0031123 RNA 3'-end processing
2.13 1.51e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.70 1.61e-02 GO:0006260 DNA replication
1.53 1.83e-02 GO:0070647 protein modification by small protein conjugation or removal
2.21 1.85e-02 GO:0031124 mRNA 3'-end processing
1.18 1.92e-02 GO:0010468 regulation of gene expression
1.64 1.97e-02 GO:0033365 protein localization to organelle
1.31 2.03e-02 GO:0043933 macromolecular complex subunit organization
1.31 2.04e-02 GO:0006351 transcription, DNA-dependent
2.30 2.10e-02 GO:0050434 positive regulation of viral transcription
1.56 2.23e-02 GO:0010608 posttranscriptional regulation of gene expression
1.14 2.25e-02 GO:0031323 regulation of cellular metabolic process
1.52 2.40e-02 GO:0044257 cellular protein catabolic process
1.65 2.46e-02 GO:0006605 protein targeting
2.05 2.47e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.05 2.47e-02 GO:0071779 G1/S transition checkpoint
1.60 2.55e-02 GO:0016567 protein ubiquitination
1.55 2.75e-02 GO:0048285 organelle fission
2.13 3.09e-02 GO:0033238 regulation of cellular amine metabolic process
2.13 3.09e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.13 3.09e-02 GO:0071158 positive regulation of cell cycle arrest
1.57 3.11e-02 GO:0032446 protein modification by small protein conjugation
1.73 3.21e-02 GO:0010498 proteasomal protein catabolic process
1.73 3.21e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.10 3.27e-02 GO:0051352 negative regulation of ligase activity
2.10 3.27e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.79 3.62e-02 GO:0045333 cellular respiration
1.48 3.91e-02 GO:0016568 chromatin modification
1.54 4.34e-02 GO:0000087 M phase of mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 6.40e-42 GO:0044424 intracellular part
1.14 2.42e-41 GO:0005622 intracellular
1.21 3.77e-39 GO:0043231 intracellular membrane-bounded organelle
1.21 3.83e-39 GO:0043227 membrane-bounded organelle
1.31 8.30e-37 GO:0005634 nucleus
1.55 7.25e-36 GO:0044428 nuclear part
1.17 1.35e-33 GO:0043229 intracellular organelle
1.59 1.89e-33 GO:0031981 nuclear lumen
1.17 5.50e-33 GO:0043226 organelle
1.50 6.89e-31 GO:0070013 intracellular organelle lumen
1.48 2.39e-30 GO:0031974 membrane-enclosed lumen
1.47 1.90e-28 GO:0043233 organelle lumen
2.07 2.53e-26 GO:0030529 ribonucleoprotein complex
1.24 6.93e-22 GO:0044446 intracellular organelle part
1.23 5.23e-21 GO:0044422 organelle part
1.55 6.51e-21 GO:0005654 nucleoplasm
1.29 7.95e-18 GO:0032991 macromolecular complex
1.87 1.51e-17 GO:0005730 nucleolus
2.58 2.65e-14 GO:0005681 spliceosomal complex
1.30 2.43e-12 GO:0043228 non-membrane-bounded organelle
1.30 2.43e-12 GO:0043232 intracellular non-membrane-bounded organelle
2.77 4.22e-10 GO:0071013 catalytic step 2 spliceosome
1.11 1.07e-09 GO:0005737 cytoplasm
1.49 8.75e-08 GO:0044451 nucleoplasm part
1.87 2.12e-07 GO:0016604 nuclear body
1.26 4.44e-07 GO:0005829 cytosol
1.33 1.48e-06 GO:0005739 mitochondrion
2.97 2.44e-06 GO:0015030 Cajal body
1.45 2.81e-06 GO:0031967 organelle envelope
1.44 3.70e-06 GO:0031975 envelope
1.46 4.50e-06 GO:0044429 mitochondrial part
1.04 7.79e-06 GO:0044464 cell part
1.04 8.45e-06 GO:0005623 cell
1.20 9.10e-06 GO:0043234 protein complex
1.52 4.99e-05 GO:0005740 mitochondrial envelope
1.46 5.13e-05 GO:0005694 chromosome
3.35 7.61e-05 GO:0044452 nucleolar part
1.11 7.86e-05 GO:0044444 cytoplasmic part
1.51 1.55e-04 GO:0031966 mitochondrial membrane
1.55 5.01e-04 GO:0019866 organelle inner membrane
1.67 9.65e-04 GO:0000228 nuclear chromosome
1.56 1.19e-03 GO:0005743 mitochondrial inner membrane
2.71 1.41e-03 GO:0009295 nucleoid
2.71 1.41e-03 GO:0042645 mitochondrial nucleoid
2.20 2.09e-03 GO:0000502 proteasome complex
1.85 2.55e-03 GO:0044455 mitochondrial membrane part
2.79 2.56e-03 GO:0030532 small nuclear ribonucleoprotein complex
1.70 2.60e-03 GO:0005840 ribosome
1.43 2.69e-03 GO:0044427 chromosomal part
1.84 4.98e-03 GO:0016607 nuclear speck
1.67 8.27e-03 GO:0044454 nuclear chromosome part
3.90 9.61e-03 GO:0005732 small nucleolar ribonucleoprotein complex
1.99 1.19e-02 GO:0000790 nuclear chromatin
1.68 1.48e-02 GO:0044445 cytosolic part
2.82 4.99e-02 GO:0005689 U12-type spliceosomal complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.36 3.22e-22 GO:0003676 nucleic acid binding
1.75 2.35e-21 GO:0003723 RNA binding
1.13 4.91e-10 GO:0005515 protein binding
1.06 3.57e-05 GO:0005488 binding
1.22 5.32e-05 GO:0000166 nucleotide binding
1.23 7.35e-05 GO:0003677 DNA binding
1.87 1.77e-04 GO:0008168 methyltransferase activity
1.80 7.71e-04 GO:0016741 transferase activity, transferring one-carbon groups
2.02 7.85e-04 GO:0008026 ATP-dependent helicase activity
2.02 7.85e-04 GO:0070035 purine NTP-dependent helicase activity
1.87 1.45e-03 GO:0004386 helicase activity
1.11 2.14e-03 GO:0003824 catalytic activity
1.57 2.74e-03 GO:0042623 ATPase activity, coupled
1.50 3.61e-03 GO:0016887 ATPase activity
2.05 6.24e-03 GO:0008135 translation factor activity, nucleic acid binding
1.32 1.50e-02 GO:0017111 nucleoside-triphosphatase activity
1.21 2.98e-02 GO:0005524 ATP binding
1.20 4.64e-02 GO:0032559 adenyl ribonucleotide binding