Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.727


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPAchr21_+_260296020.861.8e-05Click!
ELK1chrX_-_473948080.731.3e-03Click!
GABPB1chr15_-_484345670.467.1e-02Click!
ELK4chr1_-_2038674020.332.2e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_99536214 5.031 NM_182776
 MCM7
minichromosome maintenance complex component 7
chr13_-_45654296 4.726 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_38046270 4.444 YRDC
yrdC domain containing (E. coli)
chr3_+_181802592 4.324 NM_001042601
NM_133462
 TTC14

tetratricopeptide repeat domain 14

chr12_+_118590039 4.048 NM_006253
 PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_38046433 3.894 YRDC
yrdC domain containing (E. coli)
chr1_-_38046410 3.884 YRDC
yrdC domain containing (E. coli)
chr10_-_43212681 3.752 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr7_-_128482059 3.746 TNPO3
transportin 3
chr21_-_32906729 3.731 NM_021254
 C21orf59
chromosome 21 open reading frame 59
chr7_-_128482354 3.484 TNPO3
transportin 3
chr7_-_2248315 3.462 FTSJ2
FtsJ homolog 2 (E. coli)
chr13_-_45654327 3.408 NM_002298
 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_32906528 3.284 C21orf59
chromosome 21 open reading frame 59
chr6_+_170705345 3.232 NM_001172085
NM_003194
 TBP

TATA box binding protein

chr9_-_137992766 3.218 UBAC1
UBA domain containing 1
chr1_-_38228179 3.215 NM_006802
 SF3A3
splicing factor 3a, subunit 3, 60kDa
chr7_-_2248348 3.204 NM_013393
 FTSJ2
FtsJ homolog 2 (E. coli)
chr4_+_110956085 3.196 NM_018983
NM_032993
 GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr9_-_137992967 3.191 NM_016172
 UBAC1
UBA domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 139 entries
enrichment   p-value GO term description
3.21 1.17e-04 GO:0000387 spliceosomal snRNP assembly
3.05 1.00e-03 GO:0006626 protein targeting to mitochondrion
3.04 2.65e-04 GO:0000245 spliceosome assembly
2.97 1.51e-05 GO:0006369 termination of RNA polymerase II transcription
2.94 2.43e-03 GO:0072655 establishment of protein localization in mitochondrion
2.84 5.52e-03 GO:0070585 protein localization in mitochondrion
2.70 3.03e-09 GO:0022618 ribonucleoprotein complex assembly
2.67 6.31e-24 GO:0000375 RNA splicing, via transesterification reactions
2.67 3.17e-23 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.67 3.17e-23 GO:0000398 nuclear mRNA splicing, via spliceosome
2.65 1.11e-07 GO:0006353 transcription termination, DNA-dependent
2.56 4.37e-08 GO:0071826 ribonucleoprotein complex subunit organization
2.54 1.57e-07 GO:0000216 M/G1 transition of mitotic cell cycle
2.49 3.49e-05 GO:0006302 double-strand break repair
2.49 2.43e-04 GO:0006406 mRNA export from nucleus
2.47 4.60e-18 GO:0022613 ribonucleoprotein complex biogenesis
2.42 1.54e-04 GO:0006405 RNA export from nucleus
2.40 3.95e-17 GO:0071843 cellular component biogenesis at cellular level
2.38 1.57e-09 GO:0042254 ribosome biogenesis
2.38 2.82e-06 GO:0006364 rRNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 55 entries
enrichment   p-value GO term description
3.90 9.61e-03 GO:0005732 small nucleolar ribonucleoprotein complex
3.35 7.61e-05 GO:0044452 nucleolar part
2.97 2.44e-06 GO:0015030 Cajal body
2.82 4.99e-02 GO:0005689 U12-type spliceosomal complex
2.79 2.56e-03 GO:0030532 small nuclear ribonucleoprotein complex
2.77 4.22e-10 GO:0071013 catalytic step 2 spliceosome
2.71 1.41e-03 GO:0009295 nucleoid
2.71 1.41e-03 GO:0042645 mitochondrial nucleoid
2.58 2.65e-14 GO:0005681 spliceosomal complex
2.20 2.09e-03 GO:0000502 proteasome complex
2.07 2.53e-26 GO:0030529 ribonucleoprotein complex
1.99 1.19e-02 GO:0000790 nuclear chromatin
1.87 1.51e-17 GO:0005730 nucleolus
1.87 2.12e-07 GO:0016604 nuclear body
1.85 2.55e-03 GO:0044455 mitochondrial membrane part
1.84 4.98e-03 GO:0016607 nuclear speck
1.70 2.60e-03 GO:0005840 ribosome
1.68 1.48e-02 GO:0044445 cytosolic part
1.67 9.65e-04 GO:0000228 nuclear chromosome
1.67 8.27e-03 GO:0044454 nuclear chromosome part

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
2.05 6.24e-03 GO:0008135 translation factor activity, nucleic acid binding
2.02 7.85e-04 GO:0008026 ATP-dependent helicase activity
2.02 7.85e-04 GO:0070035 purine NTP-dependent helicase activity
1.87 1.77e-04 GO:0008168 methyltransferase activity
1.87 1.45e-03 GO:0004386 helicase activity
1.80 7.71e-04 GO:0016741 transferase activity, transferring one-carbon groups
1.75 2.35e-21 GO:0003723 RNA binding
1.57 2.74e-03 GO:0042623 ATPase activity, coupled
1.50 3.61e-03 GO:0016887 ATPase activity
1.36 3.22e-22 GO:0003676 nucleic acid binding
1.32 1.50e-02 GO:0017111 nucleoside-triphosphatase activity
1.23 7.35e-05 GO:0003677 DNA binding
1.22 5.32e-05 GO:0000166 nucleotide binding
1.21 2.98e-02 GO:0005524 ATP binding
1.20 4.64e-02 GO:0032559 adenyl ribonucleotide binding
1.13 4.91e-10 GO:0005515 protein binding
1.11 2.14e-03 GO:0003824 catalytic activity
1.06 3.57e-05 GO:0005488 binding